Publicaciones (21) Publicaciones de CAROLINA GARCÍA BARROSO

2024

  1. Abordaje multidisciplinar para la prevención, la detección precoz y el tratamiento temprano de las enfermedades neurodegenerativas

    Abordaje terapéutico multidisciplinar de patologías prevalentes (Elsevier), pp. 101-120

  2. Herramientas prácticas para el abordaje multidisciplinar de las enfermedades neurodegenerativas

    Abordaje terapéutico multidisciplinar de patologías prevalentes (Elsevier), pp. 121-139

2022

  1. Health-Related Quality of Life in Spanish Schoolchildren and Its Association with the Fitness Status and Adherence to the Mediterranean Diet

    Nutrients, Vol. 14, Núm. 11

2020

  1. Nutracéuticos y fitoterapia

    Universidad Católica de Avila

2019

  1. Bromatología II

    Universidad Católica de Avila

  2. Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class i Histone Deacetylase Selective Inhibitors

    ACS Chemical Neuroscience, Vol. 10, Núm. 3, pp. 1765-1782

  3. Identificación de la sarcopenia en la práctica clínica mediante la bioimpedancia

    Revista de nutrición práctica, Año 23, pp. 33-34

  4. Multitarget Approach for the Treatment of Alzheimer's Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) Covering Diverse Selectivity Profiles

    ACS Chemical Neuroscience, Vol. 10, Núm. 9, pp. 4076-4101

  5. Taking advantage of the selectivity of histone deacetylases and phosphodiesterase inhibitors to design better therapeutic strategies to treat Alzheimer's disease

    Frontiers in Aging Neuroscience, Vol. 11, Núm. JUN

2018

  1. Bioimpedancia avanzada: de la teoría a la práctica

    Revista de nutrición práctica, Año 22, pp. 30-31

  2. Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease

    European Journal of Medicinal Chemistry, Vol. 150, pp. 506-524

2017

  1. A First-in-Class Small-Molecule that Acts as a Dual Inhibitor of HDAC and PDE5 and that Rescues Hippocampal Synaptic Impairment in Alzheimer's Disease Mice

    Neuropsychopharmacology, Vol. 42, Núm. 2, pp. 524-539

2016

  1. Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease

    Journal of Medicinal Chemistry, Vol. 59, Núm. 19, pp. 8967-9004

  2. Pharmacokinetic investigation of sildenafil using positron emission tomography and determination of its effect on cerebrospinal fluid cGMP levels

    Journal of Neurochemistry, Vol. 136, Núm. 2, pp. 403-415

2015

  1. Concomitant histone deacetylase and phosphodiesterase 5 inhibition synergistically prevents the disruption in synaptic plasticity and it reverses cognitive impairment in a mouse model of Alzheimer’s disease

    Clinical Epigenetics, Vol. 7, Núm. 1

  2. Decreased levels of guanosine 3', 5'-monophosphate (cGMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in Alzheimer's disease

    Neuropathology and Applied Neurobiology, Vol. 41, Núm. 4, pp. 471-482

2014

  1. Insulin-like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice

    EMBO Molecular Medicine, Vol. 6, Núm. 10, pp. 1246-1262

  2. Phosphodiesterase inhibition in cognitive decline

    Journal of Alzheimer's Disease, Vol. 42, pp. S561-S573

2013

  1. Tadalafil crosses the blood-brain barrier and reverses cognitive dysfunction in a mouse model of AD

    Neuropharmacology, Vol. 64, pp. 114-123

2012

  1. Phosphodiesterases as therapeutic targets for Alzheimer's disease

    ACS Chemical Neuroscience, Vol. 3, Núm. 11, pp. 832-844